Nemesis is a semi-cooperative strategy game consisting of you and your crew-mates surviving on a ship infested with hostile organisms.

To win the game, you will have to finish one of the two objectives handed to you at the start of the game and get back to Earth in one piece. You will discover many obstacles on your way: evolving swarms of Intruders (the name given to the alien organisms by the ship AI), the awful physical condition of the ship, the other players who will have their own agendas and, often, just cruel fate.

The gameplay of Nemesis is created to be full of climactic moments which, hopefully, you will discover rewarding even when your best plans are ruined and your character comes to a terrible fate.